![]() ![]() The nebulized solution may be breathed directly from the nebulizer. Usual precautions for administration of warm saturated nebulae should be observed. A heated nebulizer may be part of the nebulization assembly to provide a warm saturated atmosphere if the MUCOMYST aerosol is introduced by means of a separate unheated nebulizer. MUCOMYST should not be placed directly into the chamber of a heated (hot pot) nebulizer. Also, some hand-operated nebulizers deliver particles that are larger than optimum for inhalation therapy. Hand bulbs are not recommended for routine use for nebulizing MUCOMYST because their output is generally too small. The nebulizing equipment should be cleaned immediately after use because the residues may clog the smaller orifices or corrode metal parts. Suitable nebulizers may also be fitted for use with the various intermittent positive pressure breathing (IPPB) machines. Nebulizers may also be attached to plastic face masks or plastic mouthpieces. The nebulized solution may be inhaled directly from the nebulizer. 40 De Vilbiss (The De Vilbiss Co., Somerset, Pennsylvania) and the Bennett Twin-Jet Nebulizer (Puritan Bennett Corp., Oak at 13th, Kansas City, Missouri). Various intermittent positive pressure breathing devices nebulized MUCOMYST with a satisfactory efficiency including: No. Mitchell 2 has shown that particles less than 10 microns should be retained in the respiratory tract satisfactorily. Most of the nebulizers tested will supply a high proportion of the drug solution as particles of less than 10 microns in diameter. MUCOMYST is usually administered as fine nebulae and the nebulizer used should be capable of providing optimal quantities of a suitable range of particle sizes.Ĭommercially available nebulizers will produce nebulae of MUCOMYST satisfactory for retention in the respiratory tract.
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